The station is located near the dock of the Guadalquivir River between Torneo Street and Cristo de la Expiración Avenue. It consists of 43 platforms from which the 20 companies operating in it make more than 1,500 daily arrivals or departures. It is used by an average of 17,000 passengers per day and serves as a stopping point for the arrivals and departures of metropolitan, interurban, regional, national, and international passenger transport services.

Metropolitan services: Connections with 36 localities in the Metropolitan Area, coordinated by the Metropolitan Transport Consortium of the Seville Area.
Interurban services: Connections with the Sierra Norte.
Regional services: Connections with the provinces of Almería, Córdoba, Granada, Huelva, Jaén, and Málaga.
National services: Connections with the Autonomous Communities of Valencia, Catalonia, Extremadura, Madrid, Galicia, the Basque Country, Murcia, Asturias, and Castilla-León.
International: Connections with France, Belgium, the Netherlands, Germany, Portugal, Romania, and Morocco.